Article
Transplantation models to characterize the mechanisms of stem cell-induced islet regeneration.
Current protocols in stem cell biology - 20 Sept 2013
Bell Gillian I, Seneviratne Ayesh K, Nasri Grace N, Hess David A
Abstract excerpt
This unit describes our current knowledge regarding the isolation human bone marrow-derived progenitor cells for the paracrine stimulation of islet regeneration after transplantation into immunodeficient mouse models of diabetes. By using high aldehyde dehydrogenase (ALDH(hi) ) activity, a conserved function in multiple stem cell lineages, a mixed population of hematopoietic, endothelial, and mesenchymal...
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