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Article

Hematopoietic stem cells can be separated from leukemic cells in a subgroup of adult acute lymphoblastic leukemia patients.

Leukemia & lymphoma - 1 Jun 2017

Wang Wenwen, Foerner Elena, Buss Eike, Jauch Anna, Eckstein Volker, Wuchter Patrick, Ho Anthony D, Lutz Christoph

Abstract excerpt

In B-cell acute lymphoblastic leukemia (B-ALL) separation of normal hematopoietic stem cells (HSC) has so far been limited to a subgroup of patients. As aldehyde dehydrogenase (ALDH)-activity is enriched in various stem cells we investigated its value for HSC isolation in adult B-ALL. Based on ALDH-activity patients could be stratified in ALDH-numerous (≥1.9% ALDH+cells) and ALDH-rare (<1.9% ALDH+cells) cases. In...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27734718
DOI: 10.1080/10428194.2016.1236378

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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