Article
A newly discovered class of human hematopoietic cells with SCID-repopulating activity.
Nature medicine - 1 Sept 1998
Bhatia M, Bonnet D, Murdoch B, Gan O I, Dick J E
Abstract excerpt
The detection of primitive hematopoietic cells based on repopulation of immune-deficient mice is a powerful tool to characterize the human stem-cell compartment. Here, we identify a newly discovered human repopulating cell, distinct from previously identified repopulating cells, that initiates multilineage hematopoiesis in NOD/SCID mice. We call such cells CD34neg-SCID repopulating cells, or CD34neg-SRC....
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