Article
Characterization of cells with a high aldehyde dehydrogenase activity from cord blood and acute myeloid leukemia samples.
Stem cells (Dayton, Ohio) - 1 Jan 2000
Pearce Daniel J, Taussig David, Simpson Catherine, Allen Kirsty, Rohatiner Ama Z, Lister T Andrew, Bonnet Dominique
Abstract excerpt
Aldehyde dehydrogenase (ALDH) is a cytosolic enzyme that is responsible for the oxidation of intracellular aldehydes. Elevated levels of ALDH have been demonstrated in murine and human progenitor cells compared with other hematopoietic cells, and this is thought to be important in chemoresistance...
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