Article
A genome-wide scan of serum lipid levels in the Old Order Amish.
Atherosclerosis - 1 Mar 2004
Pollin Toni I, Hsueh Wen-Chi, Steinle Nanette I, Snitker Soren, Shuldiner Alan R, Mitchell Braxton D
Abstract excerpt
Elevated serum low density lipoprotein cholesterol (LDL-C) and triglyceride (TG) and decreased high density lipoprotein cholesterol (HDL-C) levels are established risk factors for cardiovascular disease (CVD). To identify quantitative trait loci influencing lipid levels, we conducted genome-wide linkage analyses of total serum cholesterol (TSC), HDL-C, ln-transformed TG (LNTG) and LDL-C levels in 612 individuals...
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