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Article

Familial Hypercholesterolemia and Type 2 Diabetes in the Old Order Amish.

Diabetes - 1 Jul 2017

Xu Huichun, Ryan Kathleen A, Jaworek Thomas J, Southam Lorraine, Reid Jeffrey G, Overton John D, Baras Aris, Puurunen Marja K, Zeggini Eleftheria, Taylor Simeon I, Shuldiner Alan R, Mitchell Braxton D

Abstract excerpt

Alleles associated with lower levels of LDL cholesterol (LDL-C) have recently been associated with an increased risk of type 2 diabetes (T2D), highlighting the complex relationship between LDL-C and diabetes. This observation begs the question of whether LDL-C-raising alleles are associated with a decreased risk of T2D. This issue was recently addressed in a large familial hypercholesterolemia (FH) screening...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 28428224
DOI: 10.2337/db17-0173
PMCID: PMC5482078

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APOB

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