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Article

Genome-wide scan of obesity in the Old Order Amish.

The Journal of clinical endocrinology and metabolism - 1 Mar 2001

Hsueh W C, Mitchell B D, Schneider J L, St Jean P L, Pollin T I, Ehm M G, Wagner M J, Burns D K, Sakul H, Bell C J, Shuldiner A R

Abstract excerpt

To identify the genetic determinants of typical obesity, we performed a genome-wide scan of obesity-related traits using data from the Amish. Multipoint linkage analysis was performed using a variance components procedure on body mass index (BMI), waist circumference, percentage of body fat, and serum leptin concentrations. All 672 individuals were genotyped for 357 markers in 22 autosomes. We observed modest...

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PMID: 11238509
DOI: 10.1210/jcem.86.3.7358

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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