Article
Telomere associations in interphase nuclei: possible role in maintenance of interphase chromosome topology
15 Jan 2001
Abstract excerpt
The relative sizes of individual telomeres in cultured human cells under conditions of cell cycling, replicative quiescence, cell transformation and immortalization were determined using quantitative fluorescence in situ hybridization (Q-FISH) with a telomere-specific peptide nucleic acid (PNA) probe. Results obtained from analysis of telomere length profiles (TLPs), which display the distribution of relative...
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