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Article

Telomere length measurements using digital fluorescence microscopy

1 Aug 1999

Abstract excerpt

BACKGROUND: The ends of chromosomes (telomeres) are important to maintain chromosome stability, and the loss of telomere repeat sequences has been implicated in cellular senescence and genomic instability of cancer cells. The traditional method for measuring the length of telomeres (Southern analysis) requires a large number of cells (>10(5)) and does not provide information on the telomere length of individual...

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Share to Chromosomal and Genetic Variations
Share to Genomic variations and chromosomal abnormalities
Share to Telomeres, Telomerase, and Senescence

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PMID: 10404142
DOI: 10.1002/(sici)1097-0320(19990801)36:4<267::aid-cyto1>3.0.co;2-o

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