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Article

Association of polymorphism in cytochrome P450 2D6 and N-acetyltransferase-2 with Parkinson's disease.

Disease markers - 1 Jan 2010

Singh Madhu, Khanna Vinay K, Shukla Rakesh, Parmar Devendra

Abstract excerpt

The present case-control study was carried out to investigate the association of polymorphism in cytochrome P450 2D6 (CYP2D6) and N-acteyltransferase-2 (NAT2}, that are involved in the metabolism and detoxification of chemicals causing Parkinson disease (PD) like symptoms, with PD. Our data demonstrated increased frequency of CYP2D6*2 (1749G/C and 2938C/T), CYP2D6*4 (1934G/A) and CYP2D6*10A (188C/T) polymorphisms...

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Source

Open in PubMed Open full text

Identifiers

PMID: 20364044
DOI: 10.3233/DMA-2010-0688
PMCID: PMC3833242

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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