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Article

DnaG interacts with a linker region that joins the N- and C-domains of DnaB and induces the formation of 3-fold symmetric rings.

Nucleic acids research - 1 Jan 2004

Thirlway Jenny, Turner Ian J, Gibson Christopher T, Gardiner Laurence, Brady Kevin, Allen Stephanie, Roberts Clive J, Soultanas Panos

Abstract excerpt

Loading of the replicative ring helicase onto the origin of replication (oriC) is the final outcome of a well coordinated series of events that collectively constitute a primosomal cascade. Once the ring helicase is loaded, it recruits the primase and signals the switch to the polymerization mode. The transient nature of the helicase-primase (DnaB-DnaG) interaction in the Escherichia coli system has hindered our...

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PMID: 15173380
DOI: 10.1093/nar/gkh628
PMCID: PMC434434

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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