Localization and identification of human quantitative trait loci: king harvest has surely come.

doi:10.1016/j.gde.2004.04.009

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Article

Localization and identification of human quantitative trait loci: king harvest has surely come.

Current opinion in genetics & development - 1 Jun 2004

Blangero John

Abstract excerpt

The scientific process of localization and subsequent identification of genes influencing risk of common diseases is still in its infancy. Initial localization of disease-related loci has traditionally been performed using family-based linkage methods to scan the genome. Early pronouncements of the failure of this approach for common diseases were premature and based on comparing suboptimal linkage designs with...

Topics

Gene Frequency
Genetic Linkage
Genetic Predisposition to Disease
Humans
Quantitative Trait Loci

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Open in PubMed

Identifiers

PMID: 15172664
DOI: 10.1016/j.gde.2004.04.009

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