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Article

Genetic mapping in human disease.

Science (New York, N.Y.) - 7 Nov 2008

Altshuler David, Daly Mark J, Lander Eric S

Abstract excerpt

Genetic mapping provides a powerful approach to identify genes and biological processes underlying any trait influenced by inheritance, including human diseases. We discuss the intellectual foundations of genetic mapping of Mendelian and complex traits in humans, examine lessons emerging from linkage analysis of Mendelian diseases and genome-wide association studies of common diseases, and discuss questions and...

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Share to Cloning, Molecular
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genome, Human

Share to Linkage Disequilibrium

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Share to Quantitative Trait, Heritable

Share to Selection, Genetic

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Identifiers

PMID: 18988837
DOI: 10.1126/science.1156409
PMCID: PMC2694957

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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