Article
Lack of association of interleukin-1beta polymorphism with Alzheimer's disease in the Jewish population.
Neuroscience letters - 10 Jun 2004
Rosenmann Hanna, Meiner Zeev, Dresner-Pollak Rivka, Kahana Esther, Aladjem Zoja, Grenader Tal, Wertman Eli, Abramsky Oded
Abstract excerpt
A growing body of evidence suggests that Alzheimer's disease (AD) is associated with local inflammation processes, including the activation of inflammatory cytokines. We performed a case-control association study between sporadic AD patients and the exon 5 position +3953 polymorphism in the potent pro-inflammatory cytokine, interleukin-1beta (IL-1B). Recent association studies of this locus with AD revealed...
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