Article
Association of human leucocyte DR and DQ antigens in Crohn's disease in Asian Indians: a family study.
Tropical gastroenterology : official journal of the Digestive Diseases Foundation - 1 Jan 2000
Thakur Seema, Ranjan Piyush, Ghoshal U C, Muller-Myhsok Bertam, Khan Faisal, Talwar Sudha, Agarwal Suraksha
Abstract excerpt
The pathogenesis of Crohn's disease (CD) involves an abnormal immune response to enteric bacteria in genetically susceptible individuals. There are no family studies regarding the association of CD with human leucocyte antigens (HLA) class II. In the present study, we have studied the association of HLA class II antigens in patients with CD and their first-degree relatives. Nine patients with CD and their...
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