Article
Influenza virus CTL epitopes, remarkably conserved and remarkably variable.
Vaccine - 23 Oct 2009
Rimmelzwaan Guus F, Kreijtz Joost H C M, Bodewes Rogier, Fouchier Ron A M, Osterhaus Albert D M E
Abstract excerpt
Virus-specific cytotoxic T lymphocytes (CTL) contribute to the control of virus infections including those caused by influenza viruses. Especially under circumstances when antibodies induced by previous infection or vaccination fail to recognize and neutralize the virus adequately, CTL are important and contribute to protective immunity. During epidemic outbreaks caused by antigenic drift variants and during...
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