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Article

Short upstream region drives dynamic expression of hypoxia-inducible factor 1alpha during Xenopus development.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Jun 2004

Sipe Conor W, Gruber Erika J, Saha Margaret S

Abstract excerpt

Hypoxia-inducible factor 1alpha (HIF-1alpha) plays a central role in regulating oxygen-dependent gene expression and is involved in a range of pathways implicated in cellular survival, proliferation, and development. While the posttranslational regulation of HIF-1alpha is well characterized, the relative importance of its control at the transcriptional level during development remains less clear. Although the...

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Identifiers

PMID: 15162502
DOI: 10.1002/dvdy.20049

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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