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Chromosomal aberrations and risk of cancer in humans: an epidemiologic perspective

1 Jan 2004

Abstract excerpt

The pioneering papers published more than one century ago by Theodor Boveri opened the way to extensive research on the mechanism linking chromosomal abnormalities to the pathogenesis of cancer. As a result of this effort, robust theoretical and empirical evidence correlating cytogenetic damage to early stages of cancer in humans was consolidated, and an increased cancer risk was postulated in healthy subjects...

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PMID: 15162068
DOI: 10.1159/000077519

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