Article
Chromosomal aberration frequency in lymphocytes predicts the risk of cancer: results from a pooled cohort study of 22 358 subjects in 11 countries.
Carcinogenesis - 1 Jun 2008
Bonassi Stefano, Norppa Hannu, Ceppi Marcello, Strömberg Ulf, Vermeulen Roel, Znaor Ariana, Cebulska-Wasilewska Antonina, Fabianova Eleonora, Fucic Alexandra, Gundy Sarolta, Hansteen Inger-Lise, Knudsen Lisbeth E, Lazutka Juozas, Rossner Pavel, Sram Radim J, Boffetta Paolo
Abstract excerpt
Mechanistic evidence linking chromosomal aberration (CA) to early stages of cancer has been recently supported by the results of epidemiological studies that associated CA frequency in peripheral lymphocytes of healthy individuals to future cancer incidence. To overcome the limitations of single...
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