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Article

Chromosomal abnormalities: detection and implications for cancer development.

Anticancer research - 1 Jan 2000

Dos Santos N R, Van Kessel A G

Abstract excerpt

The occurrence of chromosomal abnormalities is a common theme in carcinogenesis. A large proportion of tumours which have been characterized at the cytogenetic level carries numerical and/or structural aberrations. Numerical alterations may include acquisition or loss of specific chromosomes or dramatic changes in overall ploidy levels. Structural aberrations may include DNA amplifications or deletions,...

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PMID: 10697586

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