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Article

Impact of Types of Lymphocyte Chromosomal Aberrations on Human Cancer Risk

15 Mar 2004

Abstract excerpt

The frequency of cells with structural chromosomal aberrations (CAs) in peripheral blood lymphocytes is the first genotoxicity biomarker that has shown an association with cancer risk. CAs are usually divided into chromosome-type (CSAs) and chromatid-type aberrations (CTAs), with different mechanisms of formation. From a mechanistic point of view, it is of interest to clarify whether the cancer predictivity of...

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PMID: 15026371
DOI: 10.1158/0008-5472.can-03-3360

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