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Article

Pseudomonas aeruginosa with lasI quorum-sensing deficiency during corneal infection.

Investigative ophthalmology & visual science - 1 Jun 2004

Zhu Hua, Bandara Rani, Conibear Tim C R, Thuruthyil Sophy J, Rice Scott A, Kjelleberg Staffan, Givskov Michael, Willcox Mark D P

Abstract excerpt

PURPOSE: To understand the importance of Pseudomonas aeruginosa quorum-sensing systems in the development of corneal infection, the genotypic characteristics and pathogenesis of seven ocular isolates with low-protease and acyl homoserine lactone (AHL) activity and quorum-sensing mutants of PAO1 deficient in lasI, lasR, or rhlR were investigated in the study. METHODS: The possession of the quorum-sensing genes...

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PMID: 15161855
DOI: 10.1167/iovs.03-0980

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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