Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Pseudomonas aeruginosa PA80 is a cystic fibrosis isolate deficient in RhlRI quorum sensing.

Scientific reports - 11 Mar 2021

Ahmed Syed A K Shifat, Rudden Michelle, Elias Sabrina M, Smyth Thomas J, Marchant Roger, Banat Ibrahim M, Dooley James S G

Abstract excerpt

Pseudomonas aeruginosa uses quorum sensing (QS) to modulate the expression of several virulence factors that enable it to establish severe infections. The QS system in P. aeruginosa is complex, intricate and is dominated by two main N-acyl-homoserine lactone circuits, LasRI and RhlRI. These two QS systems work in a hierarchical fashion with LasRI at the top, directly regulating RhlRI. Together these QS circuits...

Topics

Join the communities discussing this publication.

Bacterial Proteins
Cystic Fibrosis
Gene Expression Regulation, Bacterial
Genomics
Phylogeny

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pseudomonas aeruginosa

Virulence Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 33707533
DOI: 10.1038/s41598-021-85100-0
PMCID: PMC7970962

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pseudomonas aeruginosa PA80 is a cystic fibrosis isolate deficient in RhlRI quorum sensing.PMID 33707533Read ↗

Genetic and transcriptomic characteristics of RhlR-dependent quorum sensing in cystic fibrosis isolates of <i>Pseudomonas aeruginosa</i>Semantic proximity Read ↗

Non-hierarchical, RhlR-regulated acyl-homoserine lactone quorum sensing in a cystic fibrosis isolate of <i>Pseudomonas aeruginosa</i>Semantic proximity Read ↗

LasR Variant Cystic Fibrosis Isolates Reveal an Adaptable Quorum-Sensing Hierarchy in Pseudomonas aeruginosa.Semantic proximity Read ↗

PhoPQ is an upstream regulator of quorum sensing in small colony variant subpopulations of <i>Pseudomonas aeruginosa</i>Semantic proximity Read ↗

Quorum-sensing synthase mutations re-calibrate autoinducer concentrations in clinical isolates of Pseudomonas aeruginosa to enhance pathogenesis.Semantic proximity Read ↗

Characterization of lasR-deficient clinical isolates of Pseudomonas aeruginosa.Semantic proximity Read ↗

RhlR-Regulated Acyl-Homoserine Lactone Quorum Sensing in a Cystic Fibrosis Isolate of Pseudomonas aeruginosaSemantic proximity Read ↗

Quorum-sensing synthase mutations re-calibrate autoinducer concentrations in clinical isolates of Pseudomonas aeruginosa to enhance pathogenesisSemantic proximity Read ↗

GidA posttranscriptionally regulates rhl quorum sensing in Pseudomonas aeruginosa.Semantic proximity Read ↗

The conserved coordination of acyl-homoserine lactone and PqsE signaling defines the RhlR-dependent quorum-sensing network in <i>Pseudomonas aeruginosa</i> clinical isolatesSemantic proximity Read ↗

<i>Pseudomonas aeruginosa lasR</i> Mutants Resist Phagocytosis and Alter Inflammatory Cytokine Production by Cystic Fibrosis MacrophagesSemantic proximity Read ↗

The end of the reign of a “master regulator’’? A defect in function of the LasR quorum sensing regulator is a common feature of Pseudomonas aeruginosa isolatesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.