Article
Pseudomonas aeruginosa proteases and corneal virulence.
DNA and cell biology - 1 Jan 2000
Hobden Jeffery A
Abstract excerpt
Pseudomonas aeruginosa is a common cause of corneal infections, particularly among users of soft contact lenses. Previous studies with chemically induced mutants deficient in alkaline protease (AP) or elastase (LasB) suggested that these proteases contributed to the rapid liquifactive stromal necrosis characteristic of P. aeruginosa corneal infections. Because these mutants might harbor other chromosomal changes...
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