Article
Characterization of cell-to-cell signaling-deficient Pseudomonas aeruginosa strains colonizing intubated patients.
Journal of clinical microbiology - 1 Feb 2004
Dénervaud Valérie, TuQuoc Patrick, Blanc Dominique, Favre-Bonté Sabine, Krishnapillai Viji, Reimmann Cornelia, Haas Dieter, van Delden Christian
Abstract excerpt
Cell-to-cell signaling involving N-acyl-homoserine lactone compounds termed autoinducers (AIs) is instrumental to virulence factor production and biofilm development by Pseudomonas aeruginosa. In order to determine the importance of cell-to-cell signaling during the colonization of mechanically ventilated patients, we collected 442 P. aeruginosa pulmonary isolates from 13 patients. Phenotypic characterization...
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