Article
Simultaneous pancreas-kidney transplantation in patients with type 1 diabetes reverses elevated MBL levels in association with MBL2 genotype and VEGF expression.
Diabetologia - 1 Apr 2016
Bijkerk Roel, van der Pol Pieter, Khairoun Meriem, van Gijlswijk-Jansen Danielle J, Lievers Ellen, de Vries Aiko P J, de Koning Eelco J, de Fijter Hans W, Roelen Dave L, Vossen Rolf H A M, van Zonneveld Anton Jan, van Kooten Cees, Reinders Marlies E J
Abstract excerpt
AIMS/HYPOTHESIS: High levels of circulating mannan-binding lectin (MBL) are associated with the development of diabetic nephropathy and hyperglycaemia-induced vasculopathy. Here, we aimed to assess the effect of glycaemic control on circulating levels of MBL and the relationship of these levels with vascular damage. METHODS: We assessed MBL levels and corresponding MBL2 genotype, together with vascular...
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