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MMP-3 polymorphism: Genetic marker in pathological processes (Review)

26 Jul 2010

Abstract excerpt

Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that are collectively capable of cleaving virtually all extracellular matrix (ECM) substrates and play an important role in diverse physiological and pathological processes. The activity of MMPs is controlled at multiple levels, and the transcriptional regulation of MMPs appears to represent a necessary step in its regulation. MMP-3 is...

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PMID: 21472307
DOI: 10.3892/mmr.2010.340

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