Article
Association of matrix metalloproteinase-3 -1171(5A>6A) polymorphism with cancer risk: a meta-analysis of 41 studies.
PloS one - 1 Jan 2014
Yang Xin, Hu Jing-Wen, Qiu Man-Tang, Li Ming, Yin Rong, Wang Jie, Xu Lin, Zhang Qin
Abstract excerpt
BACKGROUND AND OBJECTIVE: Evidence has shown that matrix metalloproteinases-3 (MMP3) is important for cancer progression. Recent studies about the association between the -1171(5A>6A) polymorphism in MMP3 promoter region and cancer risk have yielded conflicting results. METHODOLOGY/PRINCIPAL FINDINGS: We performed a meta-analysis of 41 studies including 11112 cases and 11091 controls to determine whether the...
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