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Article

Gene expression in gastrointestinal stromal tumors is distinguished by KIT genotype and anatomic site.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 May 2004

Antonescu Cristina R, Viale Agnes, Sarran Lisa, Tschernyavsky Sylvia J, Gonen Mithat, Segal Neil H, Maki Robert G, Socci Nicholas D, DeMatteo Ronald P, Besmer Peter

Abstract excerpt

PURPOSE: Gastrointestinal stromal tumors (GISTs) are specific KIT expressing and KIT-signaling driven mesenchymal tumors of the human digestive tract, many of which have KIT-activating mutations. Previous studies have found a relatively homogeneous gene expression profile in GIST, as compared with other histological types of sarcomas. Transcriptional heterogeneity within clinically or molecularly defined subsets...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15161681
DOI: 10.1158/1078-0432.CCR-03-0715

Genes

KIT
BCL2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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