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Article

Differential expression of KIT/PDGFRA mutant isoforms in epithelioid and mixed variants of gastrointestinal stromal tumors depends predominantly on the tumor site.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Aug 2004

Wasag Bartosz, Debiec-Rychter Maria, Pauwels Patrick, Stul Michel, Vranckx Hilde, Oosterom Allan Van, Hagemeijer Anne, Sciot Raf

Abstract excerpt

Gastrointestinal stromal tumors (GISTs) form a distinctive group of mesenchymal neoplasms, showing differentiation towards the interstitial cells of Cajal. Morphologically, GISTs vary from cellular spindle cell tumors to epithelioid or mixed, epithelioid and spindle cell variants. The genotypic features underlying the morphologic differences of GISTs with vs without epithelioid components are not well defined....

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Mutation, Missense

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Share to Proto-Oncogene Proteins c-kit

Share to Receptor, Platelet-Derived Growth Factor alpha

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Source

Identifiers

PMID: 15154005
DOI: 10.1038/modpathol.3800136

Genes

KIT
PDGFRA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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