Article
Molecular subtypes of gastrointestinal stromal tumor requiring specific treatments.
Current opinion in oncology - 1 Jul 2016
Pogorzelski Michael, Falkenhorst Johanna, Bauer Sebastian
Abstract excerpt
PURPOSE OF REVIEW: This article reviews and discusses the current literature on how molecular subtyping of gastrointestinal stromal tumor (GIST) impacts decision-making in clinical practice. RECENT FINDINGS: Genotyping has not yet been used for prognostication of localized GIST. Recent findings indicate that mutations in platelet-derived growth factor receptor alpha (PDGFRA) and stem cell growth factor receptor...
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