Article
[The anti-HBV effect and mechanism of C gene truncated mutant in vitro].
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology - 1 May 2004
Di Ya-nan, Hu Da-rong, Fan Gong-ren, Hu Xue-ling, Liu Chao-ying, Liu Yong, Wu Yi-pin
Abstract excerpt
OBJECTIVE: To explore the effect and mechanism on HBV replication in C gene truncated mutant. METHODS: Protein expression of C gene truncated vector and wild C gene vector were assay by SDS-PAGE Western blot. Constructed C gene truncated expression vector was cotransfected with wild HBV genome; virus load was detected by PCR in the culture medium and the cell. The formation of core particle was assay by Native...
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