Article
Hot spot mutations of hepatitis B virus pre-C/C gene and its promotor in Chinese patients and the clinical implications.
Chinese medical journal - 1 Feb 1999
Luo K
Abstract excerpt
OBJECTIVE: To study if the functions of C gene and its promotor are related to the pathogenesis of hepatitis B and to describe their hot spot mutations in Chinese patients. DATA SOURCES: We have studied this subject in recent years. A mini-review is based on some unpublished works. DATA SELECTION: The sequence data of C gene and core promotor (cp) of hepatitis B virus (HBV) were analysed in the asymptomatic...
Topics
- Base Sequence
- Genes, Viral
- Hepatitis B
- Hepatitis B virus
- Hepatitis B, Chronic
- Humans
- Molecular Sequence Data
- Mutation
- Promoter Regions, Genetic
- Viral Core Proteins
