Article
[Detection of C gene mutation strain in vertical transmission of hepatitis B virus and its significance].
Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] - 1 Jan 2000
Wang S, Jiang P, Peng G, Zeng N, Wang Z
Abstract excerpt
OBJECTIVE: This study aims at detecting C gene mutation strain in vertical transmission of hepatitis B virus (HBV). METHODS: HBV C gene nt 2,022 - 2,321 was directly sequenced. RESULTS: Homology of HBV nucleotide sequence and amino acid sequence in mothers, fathers and their fetus was 100%. Mutation of 2,189 and 2,288 nucleotide of C gene resulted in substitution at the 97th and 130th amino acids. CONCLUSION: C...
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