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Article

The ErbB/HER receptor protein-tyrosine kinases and cancer.

Biochemical and biophysical research communications - 18 Jun 2004

Roskoski Robert

Abstract excerpt

The ErbB/HER protein-tyrosine kinases, which include the epidermal growth factor receptor, consist of a growth-factor-binding ectodomain, a single transmembrane segment, an intracellular protein-tyrosine kinase catalytic domain, and a tyrosine-containing cytoplasmic tail. The genes for the four members of this family, ErbB1-ErbB4, are found on different human chromosomes. Null mutations of any of the ErbB family...

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Identifiers

PMID: 15158434
DOI: 10.1016/j.bbrc.2004.04.150

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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