Article
Early endodermal expression of the Xenopus Endodermin gene is driven by regulatory sequences containing essential Sox protein-binding elements.
Differentiation; research in biological diversity - 1 Apr 2004
Ahmed Nadeem, Howard Laura, Woodland Hugh R
Abstract excerpt
The Endodermin gene is expressed in the early endoderm and the Spemann organizer of Xenopus embryos. It has previously been shown to be a direct target of the early endodermal transcription factor Xsox17 (Clements et al., 2003, Mech Dev 120:337-348). Here we identify two adjacent control elements in the Endodermin promoter; these drive transcription of the gene in late-gastrula endoderm and contain consensus...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.