Article
Xsox17alpha and -beta mediate endoderm formation in Xenopus.
Cell - 31 Oct 1997
Hudson C, Clements D, Friday R V, Stott D, Woodland H R
Abstract excerpt
We have isolated two Xenopus relatives of murine Sox17 expressed in gastrula presumptive endoderm. Xsox17alpha and -beta expression can be induced in animal caps by activin, but not by FGF. Ectopic expression of these genes in animal caps induces the expression of endoderm markers; this induction is blocked by overexpression of a fusion of the Xsox17beta HMG domain to the Drosophila Engrailed repressor domain, as...
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