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The molecular basis for functional divergence of duplicated SOX factors controlling endoderm formation and left-right patterning in zebrafish

2024-02-07

Abstract excerpt

Endoderm, one of three primary germ layers of vertebrate embryos, makes major contributions to the respiratory and gastrointestinal tracts and associated organs, including liver and pancreas. In mammals, the transcription factor SOX17 is vital for endoderm organ formation and can induce endoderm progenitor identity. Duplication of ancestral sox17 in the teleost lineage produced the paralogues sox32 and sox17 i...

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Literature Corpus work
c010998b-4af3-5e8d-a09a-71fc10279afb
DOI
10.1101/2024.02.06.579092
Open publication

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The molecular basis for functional divergence of duplicated SOX factors controlling endoderm formation and left-right patterning in zebrafishDOI 10.1101/2024.02.06.579092
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