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Article

The Sox17-mCherry fusion mouse line allows visualization of endoderm and vascular endothelial development.

Genesis (New York, N.Y. : 2000) - 1 Jun 2012

Burtscher Ingo, Barkey Wenke, Schwarzfischer Michael, Theis Fabian J, Lickert Heiko

Abstract excerpt

Sox17 is a HMG-box transcription factor that has been shown to play important roles in both cardio-vascular development and endoderm formation. To analyze these processes in greater detail, we have generated a Sox17-mCherry fusion (SCF) protein by gene targeting in ES cells. SCF reporter mice are homozygous viable and faithfully reflect the endogenous Sox17 protein localization. We report that SCF positive cells...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22121118
DOI: 10.1002/dvg.20829

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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