Article
Redundant early and overlapping larval roles of Xsox17 subgroup genes in Xenopus endoderm development.
Mechanisms of development - 1 Mar 2003
Clements Debbie, Cameleyre Isabelle, Woodland Hugh R
Abstract excerpt
We have used antisense morpholino oligos to establish the developmental roles of three Xsox17 proteins in Xenopus development (Xsox17alpha(1), alpha(2) and beta). We show that their synthesis can be inhibited with modest amounts of oligo. The inhibition of each individually produces defects in late midgut development. Loss of activity of the Xsox17alpha proteins additionally inhibits hindgut formation, and...
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