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Article

The Wilms tumor suppressor-1 target gene podocalyxin is transcriptionally repressed by p53.

The Journal of biological chemistry - 6 Aug 2004

Stanhope-Baker Patricia, Kessler Patricia M, Li Wenliang, Agarwal Munna L, Williams Bryan R G

Abstract excerpt

Wilms tumors are a heterogeneous class of tumors in which Wilms tumor suppressor-1 (WT1) and the p53 tumor suppressor may be variously inactivated by mutation, reduced in expression, or even overexpressed in the wild-type state. The downstream transcriptional targets of WT1 and p53 that are critical for mediating their roles in Wilms tumorigenesis are not well defined. The WiT49 cell line is characteristic of...

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PMID: 15155752
DOI: 10.1074/jbc.M404787200

Genes

PODXL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The Wilms tumor suppressor-1 target gene podocalyxin is transcriptionally repressed by p53.PMID 15155752Read ↗

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