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Comprehensive bioinformatics analysis of the TP53 signaling pathway in Wilms’ tumor

1 Oct 2020

Abstract excerpt

BACKGROUND: Differential expression of tumor protein 53 (TP53, or p53) has been observed in multiple cancers. However, the expression levels and prognostic role of TP53 signaling pathway genes in Wilms' tumor (WT) have yet to be fully explored. METHODS: The expression levels of TP53 signaling pathway genes including TP53, mouse double minute 2 (MDM2), mouse double minute 4 (MDM4), cyclin-dependent kinase 2A...

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PMID: 33178760
DOI: 10.21037/atm-20-6047

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