Article
Induction of p21 by the Wilms' tumor suppressor gene WT1.
Cancer research - 15 Apr 1997
Englert C, Maheswaran S, Garvin A J, Kreidberg J, Haber D A
Abstract excerpt
WT1 encodes a zinc finger transcription factor that is expressed in the developing kidney and the inactivation of which leads to Wilms' tumor, a pediatric kidney cancer. We have recently shown that inducible expression of WT1 in osteosarcoma cells triggers programmed cell death, an effect that is...
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