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Article

Nephroblastoma (Wilms' tumor): a model system of aberrant renal development.

Seminars in diagnostic pathology - 1 May 1994

Re G G, Hazen-Martin D J, Sens D A, Garvin A J

Abstract excerpt

Wilms' tumor, or nephroblastoma, is a developmental malignancy of the kidney that affects approximately 1 in 10,000 children between 1 and 6 years of age. Typically, the histology of nephroblastoma reveals a disorganized renal developmental process showing blastema and epithelia randomly interspersed in varying amounts of stroma. This developmental disruption is associated with the loss of function of the tumor...

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PMID: 7809506

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Nephroblastoma (Wilms' tumor): a model system of aberrant renal development.PMID 7809506Read ↗

The molecular biology of Wilms' tumourSemantic proximity Read ↗

Wilms' tumor gene 1: lessons from the interface between kidney development and cancer.Semantic proximity Read ↗

WT1: a novel tumor suppressor gene inactivated in Wilms' tumor.Semantic proximity Read ↗

Nephron Progenitor But Not Stromal Progenitor Cells Give Rise to Wilms Tumors in Mouse Models with β-Catenin Activation or Wt1 Ablation and Igf2 Upregulation.Semantic proximity Read ↗

[Wilms' tumors and malformation complexes].Semantic proximity Read ↗

Wilms TumorSemantic proximity Read ↗

Nephroblastic neoplasms.Semantic proximity Read ↗

The tumor suppressor WT1 drives progenitor cell progression and epithelialization to prevent Wilms tumorigenesis in human kidney organoidsSemantic proximity Read ↗

Wt1 ablation and Igf2 upregulation in mice result in Wilms tumors with elevated ERK1/2 phosphorylationSemantic proximity Read ↗

Exploring the Multifaceted Role of WT1 in Kidney Development and DiseaseSemantic proximity Read ↗

The genetic factors contributing to the development of Wilm's tumor and their clinical utility in its diagnosis and prognosis.Semantic proximity Read ↗

[Genetics of renal tumors].Semantic proximity Read ↗

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