Article
Heterogeneity among Helicobacter pylori strains in expression of the outer membrane protein BabA.
Infection and immunity - 1 Jun 2004
Hennig Ewa E, Mernaugh Ray, Edl Jennifer, Cao Ping, Cover Timothy L
Abstract excerpt
The BabA adhesin of Helicobacter pylori is an outer membrane protein that binds to the fucosylated Lewis b histo-blood group antigen on the surface of gastric epithelial cells. We screened a phage-displayed ScFv (single-chain fragment variable) recombinant antibody library for antibodies reactive with a recombinant BabA fragment and identified two such antibodies. Each antibody recognized an approximately 75-kDa...
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