Article
Genotypic profile of the outer membrane proteins BabA and BabB in clinical isolates of Helicobacter pylori.
Infection and immunity - 1 Jul 2006
Colbeck Jeffrey C, Hansen Lori M, Fong Julie M, Solnick Jay V
Abstract excerpt
Helicobacter pylori BabA is the ABO blood group antigen binding adhesin, which has a closely related paralogue (BabB) whose function is unknown. PCR and DNA sequence analysis showed extensive genotypic diversity in babA and babB across different strains, as well as within a strain colonizing an individual patient. We hypothesize that diverse profiles of babA and babB reflect selective pressures for adhesion,...
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