Article
Expression of the BabA adhesin during experimental infection with Helicobacter pylori.
Infection and immunity - 1 Apr 2010
Styer Cathy M, Hansen Lori M, Cooke Cara L, Gundersen Amy M, Choi Sung Sook, Berg Douglas E, Benghezal Mohammed, Marshall Barry J, Peek Richard M, Borén Thomas, Solnick Jay V
Abstract excerpt
The Helicobacter pylori babA gene encodes an outer membrane protein that mediates binding to fucosylated ABH antigens of the ABO blood group. We recently demonstrated that BabA expression is lost during experimental infection of rhesus macaques with H. pylori J166. We sought to test the generality of this observation by comparison of different H. pylori strains and different animal hosts. Challenge of macaques...
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