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Helicobacter pylori Strains from Duodenal Ulcer Patients Exhibit Mixed babA/B Genotypes with Low Levels of BabA Adhesin and Lewis b Binding.

Digestive diseases and sciences - 1 Oct 2016

Saberi Samaneh, Schmidt Alexej, Eybpoosh Sana, Esmaili Maryam, Talebkhan Yeganeh, Mohajerani Nazanin, Oghalaie Akbar, Eshagh Hosseini Mahmoud, Mohagheghi Mohammad Ali, Bugaytova Jeanna, Borén Thomas, Mohammadi Marjan

Abstract excerpt

BACKGROUND: BabA is a Helicobacter pylori cell surface adhesin, which binds to the ABO/Le(b) histo-blood group antigens (Le(b)) and serves as a virulence factor. METHODS: H. pylori single colonies were isolated from 156 [non-ulcer dyspepsia (NUD) = 97, duodenal ulcer (DU) = 34, gastric cancer (GC) = 25)] patients. babA and babB genes were evaluated by gene/locus-specific PCR. BabA protein expression and Le(b)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 27318698
DOI: 10.1007/s10620-016-4217-z

Genes

ABO

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Helicobacter pylori Strains from Duodenal Ulcer Patients Exhibit Mixed babA/B Genotypes with Low Levels of BabA Adhesin and Lewis b Binding.PMID 27318698Read ↗

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