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Article

Redefinition of the Carbohydrate Binding Specificity of Helicobacter pylori BabA Adhesin

22 Jul 2012

Abstract excerpt

Certain Helicobacter pylori strains adhere to the human gastric epithelium using the blood group antigen-binding adhesin (BabA). All BabA-expressing H. pylori strains bind to the blood group O determinants on type 1 core chains, i.e. to the Lewis b antigen (Fucα2Galβ3(Fucα4)GlcNAc; Le(b)) and the H type 1 determinant (Fucα2Galβ3GlcNAc). Recently, BabA strains have been categorized into those recognizing only...

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PMID: 22822069
DOI: 10.1074/jbc.m112.387654

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