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Deep sequencing defines the transcriptional map of<i>L. pneumophila</i>and identifies growth phase-dependent regulated ncRNAs implicated in virulence

1 Apr 2012

Abstract excerpt

The bacterium Legionella pneumophila is found ubiquitously in aquatic environments and can cause a severe pneumonia in humans called Legionnaires' disease. How this bacterium switches from intracellular to extracellular life and adapts to different hosts and environmental conditions is only partly understood. Here we used RNA deep sequencing from exponentially (replicative) and post exponentially (virulent) grown...

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PMID: 22546937
DOI: 10.4161/rna.20270

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